{"id":56,"date":"2016-02-19T22:18:47","date_gmt":"2016-02-19T22:18:47","guid":{"rendered":"http:\/\/blog.richmond.edu\/pollocklab\/?page_id=56"},"modified":"2026-02-05T08:37:56","modified_gmt":"2026-02-05T13:37:56","slug":"publications","status":"publish","type":"page","link":"https:\/\/create.richmond.edu\/pollocklab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_slider _builder_version=&#8221;4.16&#8243; header_font=&#8221;|on|||&#8221; custom_padding=&#8221;|||&#8221; 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box_shadow_spread_tablet=&#8221;0px&#8221; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;]<\/p>\n<ul>\n<li>Parker, H.K.*; Zizzamia, B.; Pollock, J.A.\u2020 \u201cAn online interactive map of human metabolic pathways and associated genetic disorders as a tool for the biochemistry classroom.\u201d J. Chem. Ed. 2025, 102, 7, 2957-2962. doi: <a href=\"https:\/\/pubs.acs.org\/doi\/full\/10.1021\/acs.jchemed.4c01279\">10.1021\/acs.jchemed.4c01279<\/a><\/li>\n<\/ul>\n<ul>\n<li>Pollock, J.A.; Parker, H.K.* &#8220;Advances in the development of prodrugs as selective modulators of estrogen receptors.&#8221;<em> J. Endocrin. Soc.<\/em> <strong>2022<\/strong>, <em>6(12)<\/em>, bvac158. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/36381014\/\">36381014<\/a><\/li>\n<\/ul>\n<ul>\n<li>Paul, L.*; Enkhbold, K.*; Robinson, S.*; Aye, T.T.*; Chung, Y.*; Pollock, J.A.; Norris, M.R. \u201cUnravelling the role of [Ru(bpy)<sub>2<\/sub>(OH<sub>2<\/sub>)<sub>2<\/sub>]<sup>2+<\/sup> complexes in photo-activated chemotherapy.\u201d <em>J. Inorg. Biochem. <\/em><strong>2022<\/strong>, <em>235<\/em>, 111930. PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35841722\/\">35841722<\/a><\/li>\n<\/ul>\n<ul>\n<li>Airas, J.*; Bayas, C.A.*; Ousidi, A.N.; Itto, M.Y.A.; Auhmani, A.; Loubidi, M.; Esseffar, M.; Pollock, J.A.; Parish, C.A.<span style=\"font-size: 11.6667px\"> &#8220;<\/span>Investigating novel thiazolyl-indazole derivatives as scaffolds for SARS-Cov-2 M<sup>Pro<\/sup> inhibitors.&#8221;<em> Eur. J. Med. Chem. Reports <\/em><strong>2022<\/strong><em>,<\/em> <em>4<\/em>, 100034.<\/li>\n<\/ul>\n<ul>\n<li>Berndsen, R.*; Cunningham, T.*; Kaelin, L.*; Callender, M.*; Boldog, W.D.*; Viering, B.*; King, A.*; Labban, N.*; Pollock, J.A.; Miller, H.B.; Blackledge, M.S. Identification and evaluation of brominated carbazoles as a novel antibiotic adjuvant scaffold in MRSA. <em>ACS Med. Chem. Lett.<\/em> <strong>2022<\/strong>, <em>13<\/em>, 483-491. <strong><em>ACS Editor\u2019s Choice Article <\/em><\/strong>PMID: <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35295086\/\">35295086<\/a><\/li>\n<\/ul>\n<ul>\n<li>Labrecque, C.L.*; Hilton, C.N.*; Airas, J.*; Blake, A.*; Rubenstein, K.J.*; Parish, C.A.; Pollock, J.A. &#8220;Identification of phenazine-based MEMO1 small-molecule inhibitors: virtual screening, fluorescence polarization validation, and inhibition of breast cancer migration.&#8221; <em>ChemMedChem<\/em> <strong>2021<\/strong>, <em>16<\/em>, 1163-1171. PMID:\u00a0<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/33332774\/\">33332774<\/a><\/li>\n<\/ul>\n<ul>\n<li>Hughes, L.B.*; Labban, N.*; Conway, G.E.*; Pollock, J.A.; Leopold, M.C. &#8220;Adaptable xerogel-layered amperometric biosensor platforms on wire electrodes for clinically relevant measurements.&#8221; <em>Sensors<\/em> <strong>2019<\/strong>, <em>19<\/em>, 2584. PMID:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31174353\/\">31174353<\/a><\/li>\n<\/ul>\n<ul>\n<li>Park, H.*; McEachon, J.D.*, Pollock, J.A. \u201cSynthesis and characterization of hydrogen peroxide activated estrogen receptor beta ligands.\u201d <em>Bioorg. Med. Chem.<\/em><strong> 2019<\/strong>, <em>27<\/em>, 2075-2082. doi: 10.1016\/j.bmc.2019.04.003 PMID:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30967304\/\">30967304<\/a>\u00a0<strong>Graphical abstract chosen for cover<\/strong><\/li>\n<\/ul>\n<ul>\n<li>Labban, N.*; Wayu, M.B.; Steele, C.M.*; Munoz, T.S.*; Pollock, J.A.; Case, W.S.; Leopold, M.C. \u201cFirst generation amperometric biosensing of galactose with xerogel-carbon nanotube layer-by-layer assemblies.\u201d <em>Nanomaterials\u00a0<\/em><strong>2019,\u00a0<\/strong><em>9, <\/em>42.\u00a0PMID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30597967\">30597967<\/a><\/li>\n<\/ul>\n<ul>\n<li>Wayu, M.B.; Pannell, M.J.*; Labban, N.*; Case, W.S.; Pollock, J.A.; Leopold, M.C. \u201cFunctionalized carbon nanotube adsorption interfaces for electron transfer studies of galactose oxidase.\u201d <em>Bioelectrochemistry\u00a0<\/em><strong>2019,<\/strong><em>125, <\/em>116-126.\u00a0PMID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30449323\">30449323<\/a><\/li>\n<\/ul>\n<ul>\n<li>Pollock, J.A.; Sharma, N.; Ippagunta, S.K.; Redecke, V.; H\u00e4cker, H.; Katzenellenbogen, J.A.<sup>\u00a0<\/sup>\u201cTriaryl pyrazole Toll-like receptor signaling inhibitors: Structure-activity relationships governing pan- and selective signaling inhibitors.\u201d <em>ChemMedChem<\/em> <strong>2018<\/strong>, <em>13<\/em>, 2208-2216. PMID:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30117269\">30117269<\/a><\/li>\n<\/ul>\n<ul>\n<li>Newkirk, M.L.*; Rubenstein, K.J.*; Kim, J.Y.*; Labrecque, C.L.*; Airas, J.*; Taylor, C.A.*; Evans, H.E.*; McKoy, Q.*; Parish, C.A.; Pollock, J.A. &#8220;Analysis of MEMO1 binding specificity for ErbB2 using fluorescence polarization and molecular dynamics simulations.&#8221; <em>Biochemistry<\/em>\u00a0<strong>2018<\/strong>, <em>57<\/em>, 5169-5181. PMID:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30067338\">30067338\u00a0<\/a><\/li>\n<\/ul>\n<ul>\n<li>Ippagunta, S.K.; Pollock, J.A.; Sharma, N.; Lin, W.; Chen, T.; Tawaratsumida, K.; High, A.A.; Min, J.; Chen, Y.; Guy, R.K.; Redecke, V.; Katzenellenbogen, J.A.; H\u00e4cker, H. \u201cIdentification of Toll-like receptor signaling inhibitors based on selective activation of hierarchically acting signaling proteins.\u201d <em>Sci. Signal.<\/em> <strong>2018<\/strong>,<em> 11(543)<\/em>, eaaq1077. PMID:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30108181\">30108181<\/a><\/li>\n<\/ul>\n<ul>\n<li>Pannell, M.J.*; Doll, E.E.*; Labban, N.*; Wayu, M.B.; Pollock, J.A.; Leopold, M.C. &#8220;Versatile sarcosine and creatinine biosensing schemes utilizing layer-by-layer construction of carbon nanotube-chitosan composite films.&#8221; <em>J. Electroanal. Chem. <\/em><strong>2018,<\/strong><em> 814, <\/em>20-30.<\/li>\n<\/ul>\n<ul>\n<li>Christenson, J.L.; Butterfield, K.T.; Spoelstra, N.S.; Norris, J.D.; Josan, J.S.; Pollock, J.A.; McDonnell, D.P.; Katzenellenbogen, B.S.; Katzenellenbogen, J.A.; Richer, J.K. \u201cMMTV-PyMT and derived Met-1 mouse mammary tumor cells as models for studying the role of the androgen receptor in triple-negative breast cancer progression.\u201d <em>Horm. Canc.<\/em> <strong>2017, <\/strong><em>8(2),<\/em> 69-77.\u00a0PMID: <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28194662\">28194662<\/a><\/li>\n<\/ul>\n<ul>\n<li>Pollock, J.A.; Wardell, S.E.; Parent, A.A.; Stagg, D.B.; Ellison, S.J.; Alley, H.M.; Chao, C.A.; Lawrence, S.A.; Stice, J.P. Spasojevic, I.; McDonnell, D.P.; Katzenellenbogen, J.A.; Norris, J.D. &#8220;Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer.&#8221; <em>Nature Chem. Biol.<\/em> <strong>2016<\/strong>, <em>12(10),<\/em> 795-801<strong>.<\/strong> PMID:\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/27501397\">27501397<\/a><\/li>\n<\/ul>\n<ul>\n<li>Pollock, J.A.; Kim, S.H.; Katzenellenbogen, J.A. \u201cImidoyl dichlorides as new reagents for the rapid formation of 2-aminobenzimidazoles and related azoles.\u201d <em>Tetrahedron Lett.<\/em> <strong>2015<\/strong>, <em>56<\/em>, 6097-6099. PMID:\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26516292\" target=\"_blank\" rel=\"noopener\">26516292<\/a><\/li>\n<\/ul>\n<ul>\n<li>Nwachukwu, J. C.; Srinivasan, S.; Bruno, N. E.; Parent, A. A.; Hughes, T. S.; Pollock, J. A.; Gjyshi, O.; Cavett, V.; Nowak, J.; Garcia-Ordonez, R. D.; Houtman, R.; Griffin, P. R.; Kojetin, D. J.; Katzenellenbogen, J. A.; Conkright, M. D.; Nettles,\u00a0 K. W. \u201cResveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.\u201d <em>eLife <\/em><strong>2014<\/strong>, <em>3<\/em>, e02057. PMID:\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/24771768\" target=\"_blank\" rel=\"noopener\">24771768<\/a><\/li>\n<\/ul>\n<ul>\n<li>Pollock, J. A.; Larrea, M. D.; Jasper, J. S.; McDonnell, D. P.; McCafferty, D. G. \u201cLysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ER\u03b1-dependent and independent manners.\u201d <em>ACS Chem. Biol.<\/em> <strong>2012<\/strong>, <em>7,<\/em> 1221-1231. PMID:\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22533360\" target=\"_blank\" rel=\"noopener\">22533360<\/a><\/li>\n<\/ul>\n<ul>\n<li>Gooden, D. M.; Schmidt, D. M. Z.; Pollock, J. A.; Kabadi, A. M.*; McCafferty, D. G. \u201cFacile synthesis of substituted <em>trans<\/em>-2-arylcyclopropylamine inhibitors of the human histone demethylase LSD1 and monoamine oxidases A and B.\u201d \u00a0<em>Bioorg. Med. Chem. Lett.<\/em> <strong>2008<\/strong>, <em>18<\/em>, 3047-3051. PMID:\u00a0<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/18242989\" target=\"_blank\" rel=\"noopener\">18242989<\/a><\/li>\n<\/ul>\n<ul>\n<li>Pollock, J. A.*; Clark, K. M.*; Martynowicz, B. J.*; Pridgeon, M. G.*; Rycenga, M. J.*; Stolle, K. E.*; Taylor, S. K. \u201cA mild biosynthesis of lactones via enantioselective hydrolysis of hydroxynitriles.\u201d <em>Tetrahedron: Asymmetry.<\/em> <strong>2007<\/strong>, <em>18<\/em>, 1888-1892.<\/li>\n<\/ul>\n<p><em>* indicates undergraduate author<\/em><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=&#8221;4.16&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; global_colors_info=&#8221;{}&#8221; column_structure=&#8221;1_4,3_4&#8243;][et_pb_column type=&#8221;1_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_font=&#8221;|on|||&#8221; text_font_size=&#8221;18&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>\n<strong>Patents<\/strong><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;3_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; text_text_color=&#8221;#595959&#8243; background_size=&#8221;initial&#8221; background_position=&#8221;top_left&#8221; background_repeat=&#8221;repeat&#8221; use_border_color=&#8221;off&#8221; border_color=&#8221;#ffffff&#8221; border_style=&#8221;solid&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Katzenellenbogen, J.; McDonnell, D.; Norris, J.; Parent, A.; Pollock, J.; Gunther, J.; Carlson, K.; Martin, T. \u201cTetra-aryl cyclobutane inhibitors of androgen receptor action for the treatment of hormone refractory cancer.\u201d Application No. 14\/57391. Publication No. WO 2015\/048246.<\/li>\n<\/ul>\n<ul>\n<li>McCafferty, D. G.; Pollock, J. A.; Gooden, D. M.; Caron, M. G.; Gainetdinov, R. R.; Sotnikova, T. D. \u201cMethods for the treatment using arylcyclopropylamine compounds.\u201d Application No. 13\/723,971. Publication No. US 2013\/0178520 A1.<\/li>\n<\/ul>\n<ul>\n<li>McCafferty, D. G.; Pollock, J. A. \u201cArylcyclopropylamines and methods of use.\u201d Application No. 12\/792,316. Publication No. US 2010\/0324147 A1.<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Parker, H.K.*; Zizzamia, B.; Pollock, J.A.\u2020 \u201cAn online interactive map of human metabolic pathways and associated genetic disorders as a tool for the biochemistry classroom.\u201d J. Chem. Ed. 2025, 102, 7, 2957-2962. doi: 10.1021\/acs.jchemed.4c01279 Pollock, J.A.; Parker, H.K.* &#8220;Advances in the development of prodrugs as selective modulators of estrogen receptors.&#8221; J. Endocrin. 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